OLR1

GENE INFORMATION

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Gene name

OLR1 (HGNC Symbol)

Synonyms

CLEC8A, LOX-1, SCARE1

Description

Oxidized low density lipoprotein (lectin-like) receptor 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]

Chromosome

12

Cytoband

p13.2

Chromosome location (bp)

10158301 - 10172138

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000173391 (version 78.38)

Entrez gene

4973

UniProt

P78380 (UniProt - Evidence at protein level)

neXtProt

NX_P78380

Antibodypedia

OLR1 antibodies
 

PROTEIN VIEW

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OLR1-001
 
OLR1-002
 
OLR1-003
 
OLR1-005
 
OLR1-006
 
OLR1-007
 
OLR1-008
 
OLR1-009
 
OLR1-010
 
OLR1-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

OLR1-001 ENSP00000309124
ENST00000309539
P78380
Show all »
Show » Show » 273 31 No 1
OLR1-002 ENSP00000405116
ENST00000432556
P78380
Show all »
Show » Show » 181 20.2 No 1
OLR1-003 ENSP00000444457
ENST00000544577
F5GZH1
Show all »
Show » Show » 165 18.6 No 1
OLR1-005 ENSP00000445085
ENST00000543993
B7ZAN8
Show all »
Show » 77 8.7 No 0
OLR1-006 ENSP00000444068
ENST00000543414
F5H001
Show all »
Show » Show » 104 12 No 0
OLR1-007 ENSP00000442389
ENST00000539518
F5H7N8
Show all »
Show » Show » 214 24.5 No 0
OLR1-008 ENSP00000439251
ENST00000545927
P78380
Show all »
Show » Show » 189 21.4 No 1
OLR1-009 ENSP00000438925
ENST00000538745
J3QTI8
Show all »
Show » Show » 122 14.3 No 0
OLR1-010 ENSP00000340572
ENST00000339968
J3QTI8
Show all »
Show » Show » 104 12.1 No 0
OLR1-013 ENSP00000438744
ENST00000538873
F5H0N6
Show all »
Show » 57 6.7 No 0