SAA1

GENE INFORMATION

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Gene name

SAA1 (HGNC Symbol)

Synonyms

PIG4, SAA, TP53I4

Description

Serum amyloid A1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Jun 2012]

Chromosome

11

Cytoband

p15.1

Chromosome location (bp)

18266174 - 18269977

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000173432 (version 78.38)

Entrez gene

6288

UniProt

P0DJI8 (UniProt - Evidence at protein level)

neXtProt

NX_P0DJI8

Antibodypedia

SAA1 antibodies
 

PROTEIN VIEW

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SAA1-001
 
SAA1-002
 
SAA1-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SAA1-001 ENSP00000348918
ENST00000356524
P0DJI8
Show all »
Show » Show » 122 13.5 Yes 0
SAA1-002 ENSP00000436866
ENST00000532858
E9PQD6
Show all »
Show » Show » 122 13.5 Yes 0
SAA1-003 ENSP00000384906
ENST00000405158
P0DJI8
Show all »
Show » Show » 122 13.5 Yes 0