NET1

GENE INFORMATION

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Gene name

NET1 (HGNC Symbol)

Synonyms

ARHGEF8, NET1A

Description

Neuroepithelial cell transforming 1 (HGNC Symbol)

Entrez gene summary

This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

Chromosome

10

Cytoband

p15.1

Chromosome location (bp)

5412551 - 5458463

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000173848 (version 78.38)

Entrez gene

10276

UniProt

Q7Z628 (UniProt - Evidence at protein level)

neXtProt

NX_Q7Z628

Antibodypedia

NET1 antibodies
 

PROTEIN VIEW

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NET1-003
 
NET1-005
 
NET1-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NET1-003 ENSP00000403101
ENST00000449083
Q5SQI6
Show all »
Show » Show » 160 18.5 No 0
NET1-005 ENSP00000347134
ENST00000355029
Q7Z628
Show all »
Show » Show » 596 67.7 No 0
NET1-006 ENSP00000369717
ENST00000380359
Q7Z628
Show all »
Show » Show » 542 61.9 No 0