DDX23

GENE INFORMATION

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Gene name

DDX23 (HGNC Symbol)

Synonyms

prp28, PRPF28, SNRNP100, U5-100K

Description

DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q13.12

Chromosome location (bp)

48829764 - 48852842

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000174243 (version 78.38)

Entrez gene

9416

UniProt

Q9BUQ8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BUQ8

Antibodypedia

DDX23 antibodies
 

PROTEIN VIEW

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DDX23-001
 
DDX23-004
 
DDX23-005
 
DDX23-019
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DDX23-001 ENSP00000310723
ENST00000308025
Q9BUQ8
Show all »
Show » Show » 820 95.6 No 0
DDX23-004 ENSP00000449639
ENST00000552512
F8VVA2
Show all »
Show » Show » 182 21.8 No 0
DDX23-005 ENSP00000446948
ENST00000551468
F8W1J5
Show all »
Show » 138 16.8 No 0
DDX23-019 ENSP00000449657
ENST00000550834
H0YIL9
Show all »
Show » 259 30.1 No 0