SLC22A1

GENE INFORMATION

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Gene name

SLC22A1 (HGNC Symbol)

Synonyms

OCT1

Description

Solute carrier family 22 (organic cation transporter), member 1 (HGNC Symbol)

Entrez gene summary

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

q25.3

Chromosome location (bp)

160121789 - 160158718

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000175003 (version 78.38)

Entrez gene

6580

UniProt

O15245 (UniProt - Evidence at protein level)

neXtProt

NX_O15245

Antibodypedia

SLC22A1 antibodies
 

PROTEIN VIEW

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SLC22A1-001
 
SLC22A1-005
 
SLC22A1-006
 
SLC22A1-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC22A1-001 ENSP00000355930
ENST00000366963
O15245
Show all »
Show » Show » 554 61.2 No >9
SLC22A1-005 ENSP00000440105
ENST00000540443
F5GY86
Show all »
Show » 48 5.4 No 0
SLC22A1-006 ENSP00000318103
ENST00000324965
O15245
Show all »
Show » Show » 506 56.1 No >9
SLC22A1-007 ENSP00000409557
ENST00000457470
O15245
Show all »
Show » Show » 483 53.6 No >9