CCNE2

GENE INFORMATION

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Gene name

CCNE2 (HGNC Symbol)

Synonyms

CYCE2

Description

Cyclin E2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

q22.1

Chromosome location (bp)

94879770 - 94896678

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000175305 (version 78.38)

Entrez gene

9134

UniProt

O96020 (UniProt - Evidence at protein level)

neXtProt

NX_O96020

Antibodypedia

CCNE2 antibodies
 

PROTEIN VIEW

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CCNE2-001
 
CCNE2-003
 
CCNE2-009
 
CCNE2-201
 
CCNE2-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCNE2-001 ENSP00000429089
ENST00000520509
O96020
Show all »
Show » Show » 404 46.8 No 0
CCNE2-003 ENSP00000379437
ENST00000396133
Q8WUE3
Show all »
Show » Show » 374 43.5 No 0
CCNE2-009 ENSP00000430060
ENST00000524224
Show » 152 17.8 No 0
CCNE2-201 ENSP00000309181
ENST00000308108
O96020
Show all »
Show » Show » 404 46.8 No 0
CCNE2-202 ENSP00000479777
ENST00000611101
I6L961
Show all »
Show » Show » 296 34.3 No 0