PHYKPL

GENE INFORMATION

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Gene name

PHYKPL (HGNC Symbol)

Synonyms

AGXT2L2, MGC15875

Description

5-phosphohydroxy-L-lysine phospho-lyase (HGNC Symbol)

Entrez gene summary

This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Chromosome

5

Cytoband

q35.3

Chromosome location (bp)

178208497 - 178232791

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000175309 (version 78.38)

Entrez gene

85007

UniProt

Q8IUZ5 (UniProt - Evidence at protein level)

neXtProt

NX_Q8IUZ5

Antibodypedia

PHYKPL antibodies
 

PROTEIN VIEW

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PHYKPL-001
 
PHYKPL-010
 
PHYKPL-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PHYKPL-001 ENSP00000310978
ENST00000308158
Q8IUZ5
Show all »
Show » Show » 450 49.7 No 0
PHYKPL-010 ENSP00000421810
ENST00000476170
D6RAR0
Show all »
Show » Show » 123 13.9 No 0
PHYKPL-011 ENSP00000321290
ENST00000323594
H7BXR0
Show all »
Show » Show » 219 24.7 No 0