COX8A

GENE INFORMATION

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Gene name

COX8A (HGNC Symbol)

Synonyms

COX, COX8, COX8-2, COX8L, VIII, VIII-L

Description

Cytochrome c oxidase subunit VIIIA (ubiquitous) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q13.1

Chromosome location (bp)

63974607 - 63976543

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000176340 (version 78.38)

Entrez gene

1351

UniProt

P10176 (UniProt - Evidence at protein level)

neXtProt

NX_P10176

Antibodypedia

COX8A antibodies
 

PROTEIN VIEW

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COX8A-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

COX8A-001 ENSP00000321260
ENST00000314133
P10176
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