RUFY1

GENE INFORMATION

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Gene name

RUFY1 (HGNC Symbol)

Synonyms

FLJ22251, RABIP4, ZFYVE12

Description

RUN and FYVE domain containing 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Chromosome

5

Cytoband

q35.3

Chromosome location (bp)

179550558 - 179610026

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000176783 (version 78.38)

Entrez gene

80230

UniProt

Q96T51 (UniProt - Evidence at protein level)

neXtProt

NX_Q96T51

Antibodypedia

RUFY1 antibodies
 

PROTEIN VIEW

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RUFY1-001
 
RUFY1-002
 
RUFY1-005
 
RUFY1-006
 
RUFY1-009
 
RUFY1-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RUFY1-001 ENSP00000325594
ENST00000319449
Q96T51
Show all »
Show » Show » 708 79.8 No 0
RUFY1-002 ENSP00000390025
ENST00000437570
Q96T51
Show all »
Show » Show » 600 69.1 No 0
RUFY1-005 ENSP00000377087
ENST00000393438
Q96T51
Show all »
Show » Show » 600 69.1 No 0
RUFY1-006 ENSP00000425533
ENST00000502984
Show » 220 24.3 No 0
RUFY1-009 ENSP00000426701
ENST00000508609
Show » 271 31 No 0
RUFY1-012 ENSP00000426117
ENST00000502434
Show » 328 38.2 No 0