CLDN22

GENE INFORMATION

? »

Gene name

CLDN22 (HGNC Symbol)

Synonyms

CLDN21

Description

Claudin 22 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3' UTR of the WWC2 gene (GeneID: 80014) on the opposite strand. [provided by RefSeq, Aug 2010]

Chromosome

4

Cytoband

q35.1

Chromosome location (bp)

183318194 - 183320774

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000177300 (version 78.38)

Entrez gene

53842

UniProt

Q8N7P3 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8N7P3

Antibodypedia

CLDN22 antibodies
 

PROTEIN VIEW

? »
 
 
 
CLDN22-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CLDN22-001 ENSP00000318113
ENST00000323319
Q8N7P3
Show all »
Show » Show » 220 24.5 No 3