PVRL3

GENE INFORMATION

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Gene name

PVRL3 (HGNC Symbol)

Synonyms

CD113, CDw113, DKFZP566B0846, nectin-3, PPR3, PVRR3

Description

Poliovirus receptor-related 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Chromosome

3

Cytoband

q13.13

Chromosome location (bp)

111070071 - 111275563

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000177707 (version 78.38)

Entrez gene

25945

UniProt

Q9NQS3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NQS3

Antibodypedia

PVRL3 antibodies
 

PROTEIN VIEW

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PVRL3-001
 
PVRL3-002
 
PVRL3-003
 
PVRL3-004
 
PVRL3-005
 
PVRL3-006
 
PVRL3-009
 
PVRL3-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PVRL3-001 ENSP00000321514
ENST00000319792
Q9NQS3
Show all »
Show » Show » 366 39.7 No 0
PVRL3-002 ENSP00000418070
ENST00000485303
Q9NQS3
Show all »
Show » Show » 549 61 No 1
PVRL3-003 ENSP00000420579
ENST00000493615
Q9NQS3
Show all »
Show » Show » 487 54.4 No 1
PVRL3-004 ENSP00000419829
ENST00000485506
H7C5G5
Show all »
Show » 31 3.7 No 0
PVRL3-005 ENSP00000418327
ENST00000461477
C9J795
Show all »
Show » Show » 130 13.9 No 0
PVRL3-006 ENSP00000418691
ENST00000491525
Show » 17 1.8 No 0
PVRL3-009 ENSP00000420479
ENST00000481766
C9JMW3
Show all »
Show » Show » 168 18.4 No 0
PVRL3-011 ENSP00000417572
ENST00000486596
Show » Show » 245 26.3 No 0