SOX12

GENE INFORMATION

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Gene name

SOX12 (HGNC Symbol)

Synonyms

SOX22

Description

SRY (sex determining region Y)-box 12 (HGNC Symbol)

Entrez gene summary

Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types. [provided by RefSeq, Jan 2013]

Chromosome

20

Cytoband

p13

Chromosome location (bp)

325401 - 330224

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000177732 (version 78.38)

Entrez gene

6666

UniProt

O15370 (UniProt - Evidence at transcript level)

neXtProt

NX_O15370

Antibodypedia

SOX12 antibodies
 

PROTEIN VIEW

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SOX12-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SOX12-001 ENSP00000347646
ENST00000342665
O15370
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