DMAP1

GENE INFORMATION

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Gene name

DMAP1 (HGNC Symbol)

Synonyms

DNMAP1, DNMTAP1, EAF2, FLJ11543, KIAA1425, MEAF2, SWC4

Description

DNA methyltransferase 1 associated protein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p34.1

Chromosome location (bp)

44213455 - 44220681

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000178028 (version 78.38)

Entrez gene

55929

UniProt

Q9NPF5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NPF5

Antibodypedia

DMAP1 antibodies
 

PROTEIN VIEW

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DMAP1-001
 
DMAP1-002
 
DMAP1-003
 
DMAP1-005
 
DMAP1-006
 
DMAP1-007
 
DMAP1-008
 
DMAP1-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DMAP1-001 ENSP00000354697
ENST00000361745
Q9NPF5
Show all »
Show » Show » 467 53 No 0
DMAP1-002 ENSP00000312697
ENST00000315913
Q9NPF5
Show all »
Show » Show » 467 53 No 0
DMAP1-003 ENSP00000361363
ENST00000372289
Q9NPF5
Show all »
Show » Show » 467 53 No 0
DMAP1-005 ENSP00000409200
ENST00000446292
Q5TG40
Show all »
Show » Show » 302 35.4 No 0
DMAP1-006 ENSP00000401099
ENST00000440641
Q5TG38
Show all »
Show » Show » 237 27.7 No 0
DMAP1-007 ENSP00000400269
ENST00000436069
Q5TG36
Show all »
Show » Show » 151 16.8 No 0
DMAP1-008 ENSP00000402494
ENST00000437511
Q5TG39
Show all »
Show » Show » 285 33.1 No 0
DMAP1-013 ENSP00000361364
ENST00000372290
Q5TG37
Show all »
Show » Show » 132 15.7 No 0