HTR1A

GENE INFORMATION

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Gene name

HTR1A (HGNC Symbol)

Synonyms

5-HT1A, ADRB2RL1, ADRBRL1

Description

5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled (HGNC Symbol)

Entrez gene summary

This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]

Chromosome

5

Cytoband

q12.3

Chromosome location (bp)

63960356 - 63962507

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000178394 (version 78.38)

Entrez gene

3350

UniProt

P08908 (UniProt - Evidence at protein level)

neXtProt

NX_P08908

Antibodypedia

HTR1A antibodies
 

PROTEIN VIEW

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HTR1A-001
 
HTR1A-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HTR1A-001 ENSP00000316244
ENST00000323865
P08908
Show all »
Show » Show » 422 46.1 No 7
HTR1A-003 ENSP00000423433
ENST00000506598
D6RA34
Show all »
Show » Show » 42 4.3 No 0