COX14

GENE INFORMATION

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Gene name

COX14 (HGNC Symbol)

Synonyms

C12orf62, MGC14288

Description

Cytochrome c oxidase assembly homolog 14 (S. cerevisiae) (HGNC Symbol)

Entrez gene summary

This gene encodes a small single-pass transmembrane protein that localizes to mitochondria. This protein may play a role in coordinating the early steps of cytochrome c oxidase (COX; also known as complex IV) subunit assembly and, in particular, the synthesis and assembly of the COX I subunit of the holoenzyme. Mutations in this gene have been associated with mitochondrial complex IV deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

Chromosome

12

Cytoband

q13.12

Chromosome location (bp)

50111979 - 50120457

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000178449 (version 78.38)

Entrez gene

84987

UniProt

Q96I36 (UniProt - Evidence at protein level)

neXtProt

NX_Q96I36

Antibodypedia

COX14 antibodies
 

PROTEIN VIEW

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COX14-001
 
COX14-002
 
COX14-003
 
COX14-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

COX14-001 ENSP00000446524
ENST00000550487
Q96I36
Show all »
Show » Show » 57 6.6 No 1
COX14-002 ENSP00000326052
ENST00000317943
Q96I36
Show all »
Show » Show » 57 6.6 No 1
COX14-003 ENSP00000447776
ENST00000548985
Q96I36
Show all »
Show » Show » 57 6.6 No 1
COX14-004 ENSP00000450331
ENST00000550654
Q96I36
Show all »
Show » Show » 57 6.6 No 1