COX5A

GENE INFORMATION

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Gene name

COX5A

Synonyms

Description

Cytochrome c oxidase subunit Va (HGNC Symbol)

Entrez gene summary

Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22. [provided by RefSeq, Jul 2008]

Chromosome

15

Cytoband

q24.2

Chromosome location (bp)

74919791 - 74938168

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000178741 (version 78.38)

Entrez gene

9377

UniProt

P20674 (UniProt - Evidence at protein level)

neXtProt

NX_P20674

Antibodypedia

COX5A antibodies
 

PROTEIN VIEW

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COX5A-001
 
COX5A-002
 
COX5A-003
 
COX5A-004
 
COX5A-005
 
COX5A-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

COX5A-001 ENSP00000317780
ENST00000322347
P20674
Show all »
Show » Show » 150 16.8 No 0
COX5A-002 ENSP00000456314
ENST00000568517
H3BRM5
Show all »
Show » Show » 69 7.8 No 0
COX5A-003 ENSP00000455053
ENST00000568783
H3BNX8
Show all »
Show » Show » 153 17.2 No 0
COX5A-004 ENSP00000456386
ENST00000564811
P20674
Show all »
Show » Show » 150 16.8 No 0
COX5A-005 ENSP00000457974
ENST00000567270
H3BV69
Show all »
Show » Show » 111 12.1 No 0
COX5A-006 ENSP00000456253
ENST00000562233
H3BRI0
Show all »
Show » Show » 84 9.3 No 0