CYP11B2

GENE INFORMATION

? »

Gene name

CYP11B2 (HGNC Symbol)

Synonyms

ALDOS, CPN2, CYP11B, CYP11BL, P-450C18, P450aldo

Description

Cytochrome P450, family 11, subfamily B, polypeptide 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

q24.3

Chromosome location (bp)

142910559 - 142917843

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000179142 (version 78.38)

Entrez gene

1585

UniProt

P19099 (UniProt - Evidence at protein level)

neXtProt

NX_P19099

Antibodypedia

CYP11B2 antibodies
 

PROTEIN VIEW

? »
 
 
 
CYP11B2-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CYP11B2-001 ENSP00000325822
ENST00000323110
P19099
Show all »
Show » Show » 503 57.6 No 0