GEMIN4

GENE INFORMATION

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Gene name

GEMIN4 (HGNC Symbol)

Synonyms

DKFZP434B131, DKFZP434D174, HC56, HCAP1, HHRF-1, p97

Description

Gem (nuclear organelle) associated protein 4 (HGNC Symbol)

Entrez gene summary

The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

p13.3

Chromosome location (bp)

744414 - 753999

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000179409 (version 78.38)

Entrez gene

50628

UniProt

P57678 (UniProt - Evidence at protein level)

neXtProt

NX_P57678

Antibodypedia

GEMIN4 antibodies
 

PROTEIN VIEW

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GEMIN4-001
 
GEMIN4-002
 
GEMIN4-003
 
GEMIN4-004
 
GEMIN4-005
 
GEMIN4-006
 
GEMIN4-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GEMIN4-001 ENSP00000321706
ENST00000319004
P57678
Show all »
Show » Show » 1058 120 No 0
GEMIN4-002 ENSP00000459565
ENST00000576778
I3L2C7
Show all »
Show » 1047 118.8 No 0
GEMIN4-003 ENSP00000392460
ENST00000437269
E7EN12
Show all »
Show » 184 21.1 No 0
GEMIN4-004 ENSP00000461368
ENST00000576383
I3L4M4
Show all »
Show » 189 21.5 No 0
GEMIN4-005 ENSP00000461103
ENST00000570364
I3L4A4
Show all »
Show » 271 30.4 No 0
GEMIN4-006 ENSP00000458896
ENST00000574958
I3L1J7
Show all »
Show » 70 7.8 No 0
GEMIN4-007 ENSP00000460286
ENST00000573482
I3L399
Show all »
Show » 296 33.3 No 0