FCER1A

GENE INFORMATION

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Gene name

FCER1A (HGNC Symbol)

Synonyms

FCE1A

Description

Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide (HGNC Symbol)

Entrez gene summary

The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011]

Chromosome

1

Cytoband

q23.2

Chromosome location (bp)

159289714 - 159308224

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000179639 (version 78.38)

Entrez gene

2205

UniProt

P12319 (UniProt - Evidence at protein level)

neXtProt

NX_P12319

Antibodypedia

FCER1A antibodies
 

PROTEIN VIEW

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FCER1A-001
 
FCER1A-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FCER1A-001 ENSP00000357097
ENST00000368115
P12319
Show all »
Show » Show » 257 29.6 Yes 1
FCER1A-002 ENSP00000357096
ENST00000368114
E9PRN1
Show all »
Show » Show » 224 25.8 Yes 1