OPCML

GENE INFORMATION

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Gene name

OPCML (HGNC Symbol)

Synonyms

IGLON1, OBCAM, OPCM

Description

Opioid binding protein/cell adhesion molecule-like (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q25

Chromosome location (bp)

132414977 - 133532519

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000183715 (version 78.38)

Entrez gene

4978

UniProt

Q14982 (UniProt - Evidence at protein level)

neXtProt

NX_Q14982

Antibodypedia

OPCML antibodies
 

PROTEIN VIEW

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OPCML-001
 
OPCML-002
 
OPCML-003
 
OPCML-201
 
OPCML-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

OPCML-001 ENSP00000330862
ENST00000331898
Q14982
Show all »
Show » Show » 345 38 Yes 0
OPCML-002 ENSP00000363910
ENST00000374778
Q14982
Show all »
Show » Show » 304 33.6 No 0
OPCML-003 ENSP00000434750
ENST00000524381
Q14982
Show all »
Show » Show » 338 37.3 Yes 0
OPCML-201 ENSP00000445496
ENST00000541867
Q14982
Show all »
Show » Show » 354 38.8 Yes 0
OPCML-202 ENSP00000482061
ENST00000612177
Q14982
Show all »
Show » Show » 345 38 Yes 0