TSSC4

GENE INFORMATION

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Gene name

TSSC4

Synonyms

Description

Tumor suppressing subtransferable candidate 4 (HGNC Symbol)

Entrez gene summary

This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes; however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. This gene may play a role in malignancies and disease that involve this region. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Chromosome

11

Cytoband

p15.5

Chromosome location (bp)

2400488 - 2403878

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000184281 (version 78.38)

Entrez gene

10078

UniProt

Q9Y5U2 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y5U2

Antibodypedia

TSSC4 antibodies
 

PROTEIN VIEW

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TSSC4-001
 
TSSC4-002
 
TSSC4-003
 
TSSC4-004
 
TSSC4-005
 
TSSC4-006
 
TSSC4-007
 
TSSC4-008
 
TSSC4-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TSSC4-001 ENSP00000331087
ENST00000333256
Q9Y5U2
Show all »
Show » 329 34.3 No 0
TSSC4-002 ENSP00000370384
ENST00000380996
Q9Y5U2
Show all »
Show » 265 27.9 No 0
TSSC4-003 ENSP00000370380
ENST00000380992
A6NCC9
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Show » 127 13.8 No 0
TSSC4-004 ENSP00000396925
ENST00000437110
C9JHT9
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Show » 203 21.2 No 0
TSSC4-005 ENSP00000403475
ENST00000435795
C9JDU0
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Show » 112 11.5 No 0
TSSC4-006 ENSP00000416937
ENST00000440813
C9JJV1
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Show » 208 22 No 0
TSSC4-007 ENSP00000431430
ENST00000485682
E9PL88
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Show » 110 11.3 No 0
TSSC4-008 ENSP00000435013
ENST00000496468
E9PME3
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Show » 191 20 No 0
TSSC4-201 ENSP00000411224
ENST00000451491
Q9Y5U2
Show all »
Show » 329 34.3 No 0