PSMD13

GENE INFORMATION

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Gene name

PSMD13 (HGNC Symbol)

Synonyms

p40.5, Rpn9

Description

Proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 (HGNC Symbol)

Entrez gene summary

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

p15.5

Chromosome location (bp)

236546 - 252984

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000185627 (version 78.38)

Entrez gene

5719

UniProt

Q9UNM6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UNM6

Antibodypedia

PSMD13 antibodies
 

PROTEIN VIEW

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PSMD13-001
 
PSMD13-003
 
PSMD13-007
 
PSMD13-009
 
PSMD13-011
 
PSMD13-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PSMD13-001 ENSP00000436186
ENST00000532097
Q9UNM6
Show all »
Show » Show » 376 42.9 No 0
PSMD13-003 ENSP00000396937
ENST00000431206
Q9UNM6
Show all »
Show » Show » 378 42.9 No 0
PSMD13-007 ENSP00000333811
ENST00000352303
J3KNQ3
Show all »
Show » 349 39.8 No 0
PSMD13-009 ENSP00000433364
ENST00000528906
E9PL38
Show all »
Show » 263 29.8 No 0
PSMD13-011 ENSP00000433115
ENST00000526783
Show » 221 25 No 0
PSMD13-201 ENSP00000478756
ENST00000621534
E9PQG3
Show all »
Show » Show » 377 42.7 No 0