NAT8L

GENE INFORMATION

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Gene name

NAT8L (HGNC Symbol)

Synonyms

FLJ37478, Hcml3

Description

N-acetyltransferase 8-like (GCN5-related, putative) (HGNC Symbol)

Entrez gene summary

This gene encodes a single-pass membrane protein, which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily. This protein is a neuron-specific protein and is the N-acetylaspartate (NAA) biosynthetic enzyme, catalyzing the NAA synthesis from L-aspartate and acetyl-CoA. NAA is a major storage and transport form of acetyl coenzyme A specific to the nervous system. The gene mutation results in primary NAA deficiency (hypoacetylaspartia). [provided by RefSeq, Dec 2010]

Chromosome

4

Cytoband

p16.3

Chromosome location (bp)

2059512 - 2069089

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000185818 (version 78.38)

Entrez gene

339983

UniProt

Q8N9F0 (UniProt - Evidence at protein level)

neXtProt

NX_Q8N9F0

Antibodypedia

NAT8L antibodies
 

PROTEIN VIEW

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NAT8L-001
 
NAT8L-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NAT8L-001 ENSP00000328464
ENST00000331662
Q8N9F0
Show all »
Show » Show » 134 15.1 No 0
NAT8L-201 ENSP00000413064
ENST00000423729
Q8N9F0
Show all »
Show » Show » 302 32.8 No 1