KRT5

GENE INFORMATION

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Gene name

KRT5 (HGNC Symbol)

Synonyms

EBS2, KRT5A

Description

Keratin 5 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q13.13

Chromosome location (bp)

52514575 - 52520687

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000186081 (version 78.38)

Entrez gene

3852

UniProt

P13647 (UniProt - Evidence at protein level)

neXtProt

NX_P13647

Antibodypedia

KRT5 antibodies
 

PROTEIN VIEW

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KRT5-001
 
KRT5-003
 
KRT5-004
 
KRT5-005
 
KRT5-007
 
KRT5-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KRT5-001 ENSP00000252242
ENST00000252242
P13647
Show all »
Show » Show » 590 62.4 No 0
KRT5-003 ENSP00000449651
ENST00000546577
F8VV57
Show all »
Show » 132 12.2 No 0
KRT5-004 ENSP00000448041
ENST00000551275
F8VU69
Show all »
Show » Show » 147 14.3 No 0
KRT5-005 ENSP00000447209
ENST00000549420
F8W0C6
Show all »
Show » Show » 179 20.7 No 0
KRT5-007 ENSP00000449783
ENST00000551188
Q9UEK9
Show all »
Show » Show » 196 21.9 No 0
KRT5-008 ENSP00000448767
ENST00000548409
Q9UEK9
Show all »
Show » Show » 201 23 No 0