HTR3D

GENE INFORMATION

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Gene name

HTR3D

Synonyms

Description

5-hydroxytryptamine (serotonin) receptor 3D, ionotropic (HGNC Symbol)

Entrez gene summary

The protein encoded this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]

Chromosome

3

Cytoband

q27.1

Chromosome location (bp)

184031544 - 184039369

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000186090 (version 78.38)

Entrez gene

200909

UniProt

Q70Z44 (UniProt - Evidence at protein level)

neXtProt

NX_Q70Z44

Antibodypedia

HTR3D antibodies
 

PROTEIN VIEW

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HTR3D-001
 
HTR3D-002
 
HTR3D-003
 
HTR3D-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HTR3D-001 ENSP00000371929
ENST00000382489
Q70Z44
Show all »
Show » Show » 454 50.2 Yes 4
HTR3D-002 ENSP00000334315
ENST00000334128
F6WC43
Show all »
Show » Show » 279 30.5 No 4
HTR3D-003 ENSP00000389268
ENST00000453435
Q70Z44
Show all »
Show » Show » 233 25.7 No 4
HTR3D-004 ENSP00000405409
ENST00000428798
Q70Z44
Show all »
Show » Show » 404 45.1 No 4