FSCN2

GENE INFORMATION

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Gene name

FSCN2 (HGNC Symbol)

Synonyms

RFSN, RP30

Description

Fascin actin-bundling protein 2, retinal (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q25.3

Chromosome location (bp)

81528396 - 81537130

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000186765 (version 78.38)

Entrez gene

25794

UniProt

O14926 (UniProt - Evidence at protein level)

neXtProt

NX_O14926

Antibodypedia

FSCN2 antibodies
 

PROTEIN VIEW

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FSCN2-001
 
FSCN2-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FSCN2-001 ENSP00000388716
ENST00000417245
O14926
Show all »
Show » Show » 492 55.1 No 0
FSCN2-003 ENSP00000334665
ENST00000334850
O14926
Show all »
Show » Show » 516 57.4 No 0