NPSR1

GENE INFORMATION

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Gene name

NPSR1 (HGNC Symbol)

Synonyms

GPR154, GPRA, PGR14

Description

Neuropeptide S receptor 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the vasopressin/oxytocin subfamily of G protein-coupled receptors. The encoded membrane protein acts as a receptor for neuropeptide S and affects a variety of cellular processes through its signaling. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Polymorphisms in this gene have also been associated with asthma susceptibility, panic disorders, inflammatory bowel disease, and rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Chromosome

7

Cytoband

p14.3

Chromosome location (bp)

34658239 - 34878332

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000187258 (version 78.38)

Entrez gene

387129

UniProt

Q6W5P4 (UniProt - Evidence at protein level)

neXtProt

NX_Q6W5P4

Antibodypedia

NPSR1 antibodies
 

PROTEIN VIEW

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NPSR1-001
 
NPSR1-002
 
NPSR1-004
 
NPSR1-006
 
NPSR1-007
 
NPSR1-008
 
NPSR1-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NPSR1-001 ENSP00000353788
ENST00000360581
Q6W5P4
Show all »
Show » Show » 371 42.7 No 7
NPSR1-002 ENSP00000352839
ENST00000359791
Q6W5P4
Show all »
Show » Show » 377 43.1 No 7
NPSR1-004 ENSP00000370953
ENST00000381542
Q6W5P4
Show all »
Show » Show » 305 35.1 No 5
NPSR1-006 ENSP00000370965
ENST00000381553
Q6W5P4
Show all »
Show » Show » 143 16.4 No 2
NPSR1-007 ENSP00000370950
ENST00000381539
Q6W5P4
Show all »
Show » Show » 390 44.3 No 7
NPSR1-008 ENSP00000434955
ENST00000465305
Q6W5P4
Show all »
Show » Show » 94 10.6 No 1
NPSR1-009 ENSP00000433258
ENST00000531252
Q6W5P4
Show all »
Show » Show » 366 42 No 7