PRKAR1B

GENE INFORMATION

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Gene name

PRKAR1B

Synonyms

Description

Protein kinase, cAMP-dependent, regulatory, type I, beta (HGNC Symbol)

Entrez gene summary

Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.[supplied by OMIM, Jun 2009]

Chromosome

7

Cytoband

p22.3

Chromosome location (bp)

549197 - 727650

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000188191 (version 78.38)

Entrez gene

5575

UniProt

P31321 (UniProt - Evidence at protein level)

neXtProt

NX_P31321

Antibodypedia

PRKAR1B antibodies
 

PROTEIN VIEW

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PRKAR1B-001
 
PRKAR1B-002
 
PRKAR1B-003
 
PRKAR1B-004
 
PRKAR1B-007
 
PRKAR1B-008
 
PRKAR1B-009
 
PRKAR1B-010
 
PRKAR1B-201
 
PRKAR1B-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRKAR1B-001 ENSP00000353415
ENST00000360274
P31321
Show all »
Show » Show » 381 43.1 No 0
PRKAR1B-002 ENSP00000385349
ENST00000403562
P31321
Show all »
Show » Show » 381 43.1 No 0
PRKAR1B-003 ENSP00000385749
ENST00000406797
P31321
Show all »
Show » Show » 381 43.1 No 0
PRKAR1B-004 ENSP00000406670
ENST00000417852
C9IZL8
Show all »
Show » 165 18.7 No 0
PRKAR1B-007 ENSP00000410414
ENST00000456696
C9J4C2
Show all »
Show » 116 13.2 No 0
PRKAR1B-008 ENSP00000402648
ENST00000430040
C9JSK5
Show all »
Show » Show » 297 33.6 No 0
PRKAR1B-009 ENSP00000383569
ENST00000400758
Show » 242 26.9 No 0
PRKAR1B-010 ENSP00000394633
ENST00000414568
C9JR00
Show all »
Show » Show » 170 18.8 No 0
PRKAR1B-201 ENSP00000440449
ENST00000537384
P31321
Show all »
Show » Show » 381 43.1 No 0
PRKAR1B-202 ENSP00000444487
ENST00000544935
P31321
Show all »
Show » Show » 381 43.1 No 0