IL1RAP

GENE INFORMATION

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Gene name

IL1RAP (HGNC Symbol)

Synonyms

C3orf13, IL-1RAcP, IL1R3

Description

Interleukin 1 receptor accessory protein (HGNC Symbol)

Entrez gene summary

Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Nov 2009]

Chromosome

3

Cytoband

q28

Chromosome location (bp)

190514051 - 190659750

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000196083 (version 78.38)

Entrez gene

3556

UniProt

Q9NPH3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NPH3

Antibodypedia

IL1RAP antibodies
 

PROTEIN VIEW

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 « 
 
IL1RAP-001
 
IL1RAP-002
 
IL1RAP-003
 
IL1RAP-005
 
IL1RAP-006
 
IL1RAP-007
 
IL1RAP-008
 
IL1RAP-010
 
IL1RAP-016
 
IL1RAP-017
 
IL1RAP-201
 
IL1RAP-202
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IL1RAP-001 ENSP00000072516
ENST00000072516
Q9NPH3
Show all »
Show » Show » 570 65.4 Yes 1
IL1RAP-002 ENSP00000401132
ENST00000439062
Q9NPH3
Show all »
Show » Show » 570 65.4 Yes 1
IL1RAP-003 ENSP00000409352
ENST00000422485
Q9NPH3
Show all »
Show » Show » 356 41 Yes 0
IL1RAP-005 ENSP00000390541
ENST00000447382
Q9NPH3
Show all »
Show » Show » 570 65.4 Yes 1
IL1RAP-006 ENSP00000314807
ENST00000317757
Q9NPH3
Show all »
Show » Show » 687 78.6 Yes 1
IL1RAP-007 ENSP00000391899
ENST00000434491
C9J9W1
Show all »
Show » Show » 215 24.3 No 0
IL1RAP-008 ENSP00000387371
ENST00000422940
Q9NPH3
Show all »
Show » Show » 356 41 Yes 0
IL1RAP-010 ENSP00000389149
ENST00000422625
C9JT28
Show all »
Show » 113 13.5 Yes 0
IL1RAP-016 ENSP00000412008
ENST00000453359
C9J1D9
Show all »
Show » 145 17.2 Yes 0
IL1RAP-017 ENSP00000414102
ENST00000412080
Show » Show » 193 21.6 No 0
IL1RAP-201 ENSP00000412053
ENST00000412504
Q9NPH3
Show all »
Show » Show » 570 65.4 Yes 1
IL1RAP-202 ENSP00000408893
ENST00000443369
Q9NPH3
Show all »
Show » Show » 687 78.6 Yes 1