ANAPC7

GENE INFORMATION

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Gene name

ANAPC7 (HGNC Symbol)

Synonyms

APC7

Description

Anaphase promoting complex subunit 7 (HGNC Symbol)

Entrez gene summary

This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]

Chromosome

12

Cytoband

q24.11

Chromosome location (bp)

110372900 - 110403730

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000196510 (version 78.38)

Entrez gene

51434

UniProt

Q9UJX3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UJX3

Antibodypedia

ANAPC7 antibodies
 

PROTEIN VIEW

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ANAPC7-001
 
ANAPC7-002
 
ANAPC7-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ANAPC7-001 ENSP00000394394
ENST00000455511
Q9UJX3
Show all »
Show » Show » 599 66.9 No 0
ANAPC7-002 ENSP00000402314
ENST00000450008
Q9UJX3
Show all »
Show » Show » 537 60 No 0
ANAPC7-010 ENSP00000450293
ENST00000552087
Q69YV3
Show all »
Show » Show » 149 16.7 No 0