SRC

GENE INFORMATION

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Gene name

SRC (HGNC Symbol)

Synonyms

ASV, c-src, SRC1

Description

SRC proto-oncogene, non-receptor tyrosine kinase (HGNC Symbol)

Entrez gene summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

q11.23

Chromosome location (bp)

37344685 - 37406050

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000197122 (version 78.38)

Entrez gene

6714

UniProt

P12931 (UniProt - Evidence at protein level)

neXtProt

NX_P12931

Antibodypedia

SRC antibodies
 

PROTEIN VIEW

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SRC-001
 
SRC-002
 
SRC-005
 
SRC-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SRC-001 ENSP00000362680
ENST00000373578
P12931
Show all »
Show » Show » 536 59.8 No 0
SRC-002 ENSP00000362668
ENST00000373567
P12931
Show all »
Show » Show » 536 59.8 No 0
SRC-005 ENSP00000362659
ENST00000373558
P12931
Show all »
Show » Show » 542 60.6 No 0
SRC-201 ENSP00000350941
ENST00000358208
P12931
Show all »
Show » Show » 536 59.8 No 0