SPN

GENE INFORMATION

? »

Gene name

SPN (HGNC Symbol)

Synonyms

CD43, GPL115, LSN

Description

Sialophorin (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response. [provided by RefSeq, Sep 2011]

Chromosome

16

Cytoband

p11.2

Chromosome location (bp)

29662979 - 29670876

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000197471 (version 78.38)

Entrez gene

6693

UniProt

P16150 (UniProt - Evidence at protein level)

neXtProt

NX_P16150

Antibodypedia

SPN antibodies
 

PROTEIN VIEW

? »
 
 
 
SPN-001
 
SPN-002
 
SPN-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SPN-001 ENSP00000378787
ENST00000395389
P16150
Show all »
Show » Show » 400 40.3 Yes 1
SPN-002 ENSP00000412907
ENST00000436527
C9JUK7
Show all »
Show » 355 36 Yes 1
SPN-201 ENSP00000353238
ENST00000360121
P16150
Show all »
Show » Show » 400 40.3 Yes 1