RPL10A

GENE INFORMATION

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Gene name

RPL10A (HGNC Symbol)

Synonyms

Csa-19, L10A, NEDD6

Description

Ribosomal protein L10a (HGNC Symbol)

Entrez gene summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L1P family of ribosomal proteins. It is located in the cytoplasm. The expression of this gene is downregulated in the thymus by cyclosporin-A (CsA), an immunosuppressive drug. Studies in mice have shown that the expression of the ribosomal protein L10a gene is downregulated in neural precursor cells during development. This gene previously was referred to as NEDD6 (neural precursor cell expressed, developmentally downregulated 6), but it has been renamed RPL10A (ribosomal protein 10a). As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

p21.31

Chromosome location (bp)

35468408 - 35470785

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000198755 (version 78.38)

Entrez gene

4736

UniProt

P62906 (UniProt - Evidence at protein level)

neXtProt

NX_P62906

Antibodypedia

RPL10A antibodies
 

PROTEIN VIEW

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RPL10A-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RPL10A-001 ENSP00000363018
ENST00000322203
P62906
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