EGFL6

GENE INFORMATION

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Gene name

EGFL6 (HGNC Symbol)

Synonyms

MAEG

Description

EGF-like-domain, multiple 6 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

p22.2

Chromosome location (bp)

13569605 - 13633575

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000198759 (version 78.38)

Entrez gene

25975

UniProt

Q8IUX8 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8IUX8

Antibodypedia

EGFL6 antibodies
 

PROTEIN VIEW

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EGFL6-002
 
EGFL6-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EGFL6-002 ENSP00000355126
ENST00000361306
Q8IUX8
Show all »
Show » Show » 553 61.3 Yes 0
EGFL6-003 ENSP00000369976
ENST00000380602
Q8IUX8
Show all »
Show » Show » 554 61.4 Yes 0