ARHGEF15

GENE INFORMATION

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Gene name

ARHGEF15 (HGNC Symbol)

Synonyms

ARGEF15, FLJ13791, KIAA0915, MGC44868, Vsm-RhoGEF

Description

Rho guanine nucleotide exchange factor (GEF) 15 (HGNC Symbol)

Entrez gene summary

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. This gene encodes a protein that functions as a specific guanine nucleotide exchange factor for RhoA. It also interacts with ephrin A4 in vascular smooth muscle cells. Two alternatively spliced transcripts variants that encode the same protein have been found for this gene. [provided by RefSeq, Aug 2010]

Chromosome

17

Cytoband

p13.1

Chromosome location (bp)

8310241 - 8322516

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000198844 (version 78.38)

Entrez gene

22899

UniProt

O94989 (UniProt - Evidence at protein level)

neXtProt

NX_O94989

Antibodypedia

ARHGEF15 antibodies
 

PROTEIN VIEW

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ARHGEF15-001
 
ARHGEF15-004
 
ARHGEF15-005
 
ARHGEF15-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARHGEF15-001 ENSP00000355026
ENST00000361926
O94989
Show all »
Show » Show » 841 91.9 No 0
ARHGEF15-004 ENSP00000464540
ENST00000579439
J3QS60
Show all »
Show » 208 21.1 No 0
ARHGEF15-005 ENSP00000462796
ENST00000583529
J3KT46
Show all »
Show » 116 12.1 No 0
ARHGEF15-201 ENSP00000412505
ENST00000421050
O94989
Show all »
Show » Show » 841 91.9 No 0