RXRB

GENE INFORMATION

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Gene name

RXRB (HGNC Symbol)

Synonyms

H-2RIIBP, NR2B2, RCoR-1

Description

Retinoid X receptor, beta (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Chromosome

6

Cytoband

p21.32

Chromosome location (bp)

33193588 - 33200688

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000204231 (version 78.38)

Entrez gene

6257

UniProt

P28702 (UniProt - Evidence at protein level)

neXtProt

NX_P28702

Antibodypedia

RXRB antibodies
 

PROTEIN VIEW

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RXRB-001
 
RXRB-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RXRB-001 ENSP00000363812
ENST00000374680
P28702
Show all »
Show » Show » 533 56.9 No 0
RXRB-002 ENSP00000363817
ENST00000374685
P28702
Show all »
Show » Show » 537 57.4 No 0