HSPA1A

GENE INFORMATION

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Gene name

HSPA1A (HGNC Symbol)

Synonyms

HSP70-1, HSPA1

Description

Heat shock 70kDa protein 1A (HGNC Symbol)

Entrez gene summary

This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

p21.33

Chromosome location (bp)

31815464 - 31817946

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000204389 (version 78.38)

Entrez gene

3303

UniProt

P08107 (UniProt - Evidence at protein level)

neXtProt

NX_P08107

Antibodypedia

HSPA1A antibodies
 

PROTEIN VIEW

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HSPA1A-001
 
HSPA1A-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HSPA1A-001 ENSP00000364802
ENST00000375651
P08107
Show all »
Show » Show » 641 70.1 No 0
HSPA1A-002 ENSP00000477378
ENST00000608703
V9GZ37
Show all »
Show » Show » 476 51.9 No 0