CSHL1

GENE INFORMATION

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Gene name

CSHL1 (HGNC Symbol)

Synonyms

CS-5, CSHP1, CSL, hCS-L, MGC149868

Description

Chorionic somatomammotropin hormone-like 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q23.3

Chromosome location (bp)

63909597 - 63918838

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000204414 (version 78.38)

Entrez gene

1444

UniProt

Q14406 (UniProt - Evidence at protein level)

neXtProt

NX_Q14406

Antibodypedia

CSHL1 antibodies
 

PROTEIN VIEW

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CSHL1-001
 
CSHL1-002
 
CSHL1-003
 
CSHL1-006
 
CSHL1-008
 
CSHL1-009
 
CSHL1-201
 
CSHL1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CSHL1-001 ENSP00000316360
ENST00000346606
Q14406
Show all »
Show » Show » 128 14.9 No 0
CSHL1-002 ENSP00000259003
ENST00000259003
I6L999
Show all »
Show » Show » 160 18.2 Yes 0
CSHL1-003 ENSP00000452900
ENST00000561003
H0YKQ4
Show all »
Show » Show » 178 19.6 No 0
CSHL1-006 ENSP00000413501
ENST00000450719
H7C3R7
Show all »
Show » Show » 167 18.6 No 0
CSHL1-008 ENSP00000402632
ENST00000438387
Q14406
Show all »
Show » Show » 139 15.9 No 0
CSHL1-009 ENSP00000309524
ENST00000309894
Q14406
Show all »
Show » Show » 222 25.4 Yes 0
CSHL1-201 ENSP00000376569
ENST00000392824
I6L999
Show all »
Show » Show » 217 24.9 Yes 0
CSHL1-202 ENSP00000483369
ENST00000611417
I6L999
Show all »
Show » Show » 217 24.9 Yes 0