NCR3

GENE INFORMATION

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Gene name

NCR3 (HGNC Symbol)

Synonyms

1C7, CD337, LY117, NKp30

Description

Natural cytotoxicity triggering receptor 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]

Chromosome

6

Cytoband

p21.33

Chromosome location (bp)

31588895 - 31592985

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000204475 (version 78.38)

Entrez gene

259197

UniProt

O14931 (UniProt - Evidence at protein level)

neXtProt

NX_O14931

Antibodypedia

NCR3 antibodies
 

PROTEIN VIEW

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NCR3-001
 
NCR3-002
 
NCR3-003
 
NCR3-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NCR3-001 ENSP00000342156
ENST00000340027
O14931
Show all »
Show » Show » 201 21.6 Yes 1
NCR3-002 ENSP00000365241
ENST00000376073
O14931
Show all »
Show » Show » 177 19.2 Yes 1
NCR3-003 ENSP00000365240
ENST00000376072
O14931
Show all »
Show » Show » 190 20.6 Yes 1
NCR3-004 ENSP00000365239
ENST00000376071
O14931
Show all »
Show » Show » 165 17.8 Yes 1