DHX16

GENE INFORMATION

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Gene name

DHX16 (HGNC Symbol)

Synonyms

DBP2, DDX16, Prp2, PRPF2

Description

DEAH (Asp-Glu-Ala-His) box polypeptide 16 (HGNC Symbol)

Entrez gene summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]

Chromosome

6

Cytoband

p21.33

Chromosome location (bp)

30653119 - 30673037

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000204560 (version 78.38)

Entrez gene

8449

UniProt

O60231 (UniProt - Evidence at protein level)

neXtProt

NX_O60231

Antibodypedia

DHX16 antibodies
 

PROTEIN VIEW

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DHX16-001
 
DHX16-002
 
DHX16-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DHX16-001 ENSP00000365625
ENST00000376442
O60231
Show all »
Show » Show » 1041 119.3 No 0
DHX16-002 ENSP00000365620
ENST00000376437
Q5SQH5
Show all »
Show » Show » 560 63.5 No 0
DHX16-003 ENSP00000399101
ENST00000415603
A2AB15
Show all »
Show » 295 34.9 No 0