PDE7A

GENE INFORMATION

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Gene name

PDE7A (HGNC Symbol)

Synonyms

HCP1

Description

Phosphodiesterase 7A (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011]

Chromosome

8

Cytoband

q13.1

Chromosome location (bp)

65717510 - 65842322

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000205268 (version 78.38)

Entrez gene

5150

UniProt

Q13946 (UniProt - Evidence at protein level)

neXtProt

NX_Q13946

Antibodypedia

PDE7A antibodies
 

PROTEIN VIEW

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PDE7A-001
 
PDE7A-003
 
PDE7A-004
 
PDE7A-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PDE7A-001 ENSP00000385632
ENST00000401827
Q13946
Show all »
Show » Show » 482 55.5 No 0
PDE7A-003 ENSP00000368730
ENST00000379419
Q13946
Show all »
Show » Show » 456 52.7 Yes 0
PDE7A-004 ENSP00000379881
ENST00000396642
Q13946
Show all »
Show » Show » 424 48.8 No 0
PDE7A-005 ENSP00000430262
ENST00000523253
E5RG23
Show all »
Show » 86 10 Yes 0