OLIG2

GENE INFORMATION

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Gene name

OLIG2 (HGNC Symbol)

Synonyms

BHLHB1, bHLHe19, OLIGO2, PRKCBP2, RACK17

Description

Oligodendrocyte lineage transcription factor 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008]

Chromosome

21

Cytoband

q22.11

Chromosome location (bp)

33025845 - 33029196

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000205927 (version 78.38)

Entrez gene

10215

UniProt

Q13516 (UniProt - Evidence at protein level)

neXtProt

NX_Q13516

Antibodypedia

OLIG2 antibodies
 

PROTEIN VIEW

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OLIG2-001
 
OLIG2-002
 
OLIG2-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

OLIG2-001 ENSP00000371794
ENST00000382357
Q13516
Show all »
Show » Show » 323 32.4 No 0
OLIG2-002 ENSP00000331040
ENST00000333337
Q13516
Show all »
Show » Show » 323 32.4 No 0
OLIG2-003 ENSP00000391183
ENST00000430860
C9J444
Show all »
Show » 62 6.1 No 0