IFITM5

GENE INFORMATION

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Gene name

IFITM5 (HGNC Symbol)

Synonyms

BRIL, fragilis4, Hrmp1

Description

Interferon induced transmembrane protein 5 (HGNC Symbol)

Entrez gene summary

This gene encodes a membrane protein thought to play a role in bone mineralization. This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195). [provided by RefSeq, Aug 2012]

Chromosome

11

Cytoband

p15.5

Chromosome location (bp)

298200 - 299526

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000206013 (version 78.38)

Entrez gene

387733

UniProt

A6NNB3 (UniProt - Evidence at protein level)

neXtProt

NX_A6NNB3

Antibodypedia

IFITM5 antibodies
 

PROTEIN VIEW

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IFITM5-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IFITM5-001 ENSP00000372059
ENST00000382614
A6NNB3
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