GPX3

GENE INFORMATION

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Gene name

GPX3

Synonyms

Description

Glutathione peroxidase 3 (plasma) (HGNC Symbol)

Entrez gene summary

This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q33.1

Chromosome location (bp)

151020438 - 151028993

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000211445 (version 78.38)

Entrez gene

2878

UniProt

P22352 (UniProt - Evidence at protein level)

neXtProt

NX_P22352

Antibodypedia

GPX3 antibodies
 

PROTEIN VIEW

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GPX3-001
 
GPX3-003
 
GPX3-004
 
GPX3-008
 
GPX3-010
 
GPX3-201
 
GPX3-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GPX3-001 ENSP00000373477
ENST00000388825
P22352
Show all »
Show » Show » 226 25.6 Yes 0
GPX3-003 ENSP00000430743
ENST00000521632
Show » Show » 174 18.9 No 0
GPX3-004 ENSP00000427873
ENST00000521650
Show » Show » 139 15.2 Yes 0
GPX3-008 ENSP00000429314
ENST00000520059
Show » Show » 79 8.7 No 0
GPX3-010 ENSP00000429709
ENST00000517973
Show » 100 11.4 Yes 0
GPX3-201 ENSP00000483660
ENST00000614343
Q6NXQ3
Show all »
Show » Show » 72 7.9 Yes 0
GPX3-202 ENSP00000484258
ENST00000622181
Q6NXQ3
Show all »
Show » Show » 225 25.4 Yes 0