CKLF

GENE INFORMATION

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Gene name

CKLF (HGNC Symbol)

Synonyms

C32, CKLF1, CKLF3, CKLF4, HSPC224, UCK-1

Description

Chemokine-like factor (HGNC Symbol)

Entrez gene summary

The product of this gene is a cytokine. Cytokines are small proteins that have an essential role in the immune and inflammatory responses. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. The protein encoded by this gene is a potent chemoattractant for neutrophils, monocytes and lymphocytes. It also can stimulate the proliferation of skeletal muscle cells. This protein may play important roles in inflammation and in the regeneration of skeletal muscle. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1).[provided by RefSeq, Feb 2011]

Chromosome

16

Cytoband

q21

Chromosome location (bp)

66552563 - 66566251

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000217555 (version 78.38)

Entrez gene

51192

UniProt

Q9UBR5 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9UBR5

Antibodypedia

CKLF antibodies
 

PROTEIN VIEW

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CKLF-001
 
CKLF-002
 
CKLF-003
 
CKLF-004
 
CKLF-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CKLF-001 ENSP00000264001
ENST00000264001
Q9UBR5
Show all »
Show » Show » 152 17.2 No 3
CKLF-002 ENSP00000264003
ENST00000351137
Q5BJH6
Show all »
Show » 99 10.9 No 2
CKLF-003 ENSP00000290771
ENST00000345436
Show » 120 13.9 No 2
CKLF-004 ENSP00000355417
ENST00000362093
Show » 67 7.7 Yes 0
CKLF-005 ENSP00000416678
ENST00000417030
Show » 113 12.9 No 2