HEPN1

GENE INFORMATION

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Gene name

HEPN1

Synonyms

Description

Hepatocellular carcinoma, down-regulated 1 (HGNC Symbol)

Entrez gene summary

This gene is expressed in the liver, and encodes a short peptide that is localized predominantly to the cytoplasm. Transient transfection studies showed that expression of this gene significantly inhibited cell growth, and it may have a role in apoptosis. Expression of this gene is downregulated or lost in hepatocellular carcinomas (HCC), suggesting that loss of this gene is involved in carcinogenesis of hepatocytes (PMID:12971969). Also to note is that this gene maps to the 3'-noncoding region of HEPACAM gene (GeneID:220296) on the antisense strand (PMID:15885354). [provided by RefSeq, Aug 2011]

Chromosome

11

Cytoband

q24.2

Chromosome location (bp)

124919244 - 124920677

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000221932 (version 78.38)

Entrez gene

641654

UniProt

Q6WQI6 (UniProt - Uncertain)

neXtProt

NX_Q6WQI6

Antibodypedia

HEPN1 antibodies
 

PROTEIN VIEW

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HEPN1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HEPN1-001 ENSP00000386143
ENST00000408930
Q6WQI6
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