FADS3

GENE INFORMATION

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Gene name

FADS3 (HGNC Symbol)

Synonyms

CYB5RP, LLCDL3

Description

Fatty acid desaturase 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q12.2

Chromosome location (bp)

61873519 - 61892051

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000221968 (version 78.38)

Entrez gene

3995

UniProt

Q9Y5Q0 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9Y5Q0

Antibodypedia

FADS3 antibodies
 

PROTEIN VIEW

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FADS3-001
 
FADS3-002
 
FADS3-006
 
FADS3-008
 
FADS3-009
 
FADS3-012
 
FADS3-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FADS3-001 ENSP00000278829
ENST00000278829
Q9Y5Q0
Show all »
Show » Show » 445 51.1 No 5
FADS3-002 ENSP00000432206
ENST00000525588
E9PS00
Show all »
Show » Show » 417 48.2 No 5
FADS3-006 ENSP00000436890
ENST00000531956
E9PQC2
Show all »
Show » Show » 199 23.1 No 4
FADS3-008 ENSP00000435597
ENST00000527379
Show » Show » 229 26.6 No 2
FADS3-009 ENSP00000432012
ENST00000525094
Show » Show » 116 13.6 No 0
FADS3-012 ENSP00000431533
ENST00000527697
E9PKP8
Show all »
Show » Show » 330 38.3 No 4
FADS3-013 ENSP00000434551
ENST00000534223
E9PPZ4
Show all »
Show » Show » 188 21.9 No 3