TWIST2

GENE INFORMATION

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Gene name

TWIST2 (HGNC Symbol)

Synonyms

bHLHa39, Dermo-1, DERMO1

Description

Twist family bHLH transcription factor 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a basic helix-loop-helix type transcription factor and shares similarity with Twist. This protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype during osteoblast development. This gene may be upregulated in certain cancers. Mutations in this gene cause focal facial dermal dysplasia 3, Setleis type. Two transcript variants encoding the same protein have been found. [provided by RefSeq, Apr 2014]

Chromosome

2

Cytoband

q37.3

Chromosome location (bp)

238848032 - 238910543

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000233608 (version 78.38)

Entrez gene

117581

UniProt

Q8WVJ9 (UniProt - Evidence at protein level)

neXtProt

NX_Q8WVJ9

Antibodypedia

TWIST2 antibodies
 

PROTEIN VIEW

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TWIST2-001
 
TWIST2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TWIST2-001 ENSP00000405176
ENST00000448943
Q8WVJ9
Show all »
Show » Show » 160 18.1 No 0
TWIST2-201 ENSP00000482581
ENST00000612363
Q8WVJ9
Show all »
Show » Show » 160 18.1 No 0