TNFRSF6B

GENE INFORMATION

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Gene name

TNFRSF6B (HGNC Symbol)

Synonyms

DcR3, M68, TR6

Description

Tumor necrosis factor receptor superfamily, member 6b, decoy (HGNC Symbol)

Entrez gene summary

This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011]

Chromosome

20

Cytoband

q13.33

Chromosome location (bp)

63696668 - 63698684

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000243509 (version 78.38)

Entrez gene

8771

UniProt

O95407 (UniProt - Evidence at protein level)

neXtProt

NX_O95407

Antibodypedia

TNFRSF6B antibodies
 

PROTEIN VIEW

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TNFRSF6B-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TNFRSF6B-001 ENSP00000359013
ENST00000369996
O95407
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