LEFTY1

GENE INFORMATION

? »

Gene name

LEFTY1 (HGNC Symbol)

Synonyms

LEFTB, LEFTYB

Description

Left-right determination factor 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q42.12

Chromosome location (bp)

225886282 - 225911382

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000243709 (version 78.38)

Entrez gene

10637

UniProt

O75610 (UniProt - Evidence at transcript level)

neXtProt

NX_O75610

Antibodypedia

LEFTY1 antibodies
 

PROTEIN VIEW

? »
 
 
 
LEFTY1-001
 
LEFTY1-002
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LEFTY1-001 ENSP00000272134
ENST00000272134
O75610
Show all »
Show » Show » 366 40.9 Yes 0
LEFTY1-002 ENSP00000479837
ENST00000492457
Show » Show » 64 7.4 No 0